The Emperor of All Maladies: A Biography of Cancer
Siddhartha Mukherjee
Published in 2011 by Fourth Estate (HarperCollins), £12.99
“There is no good or evil, only power and those who are too weak to see it.”
-Professor Quirrell to Harry Potter while explaining why he became a supporter of Lord Voldemort, in ‘Harry Potter and the Philosopher’s Stone’, JK Rowling.
The debate over the meaning of good and evil has raged amongst mankind for as long as, well, mankind’s been around. Every ancient scripture, every Disney movie, firmly reassures that good will always triumph over evil: as long as you do no wrong, you can come to no harm. As perpetual optimists, we like to stay secure among our Manichaean beliefs that sticking to the straight and narrow is a guaranteed way of staying out of trouble, resisting the sweet fruit of temptation growing on the hedges beside that straight and narrow path will keep misfortune at bay. But what happens if your own body rebels against you?
Disease is not discriminating; it can strike anyone. Yes, the risk of lifestyle illnesses can be decreased, but who is to blame if someone in the pink of health succumbs to an invisible nemesis? Two years ago, my grandma lost a hard fought battle against leukaemia, and battle’s the right word, not a cliché: fighting cancer is every bit as exhausting and emotionally difficult as guerrilla warfare. She ate a balanced diet, didn’t smoke or drink, went for power walks everyday and used no products that could be potentially carcinogenic.
Cancer came silently and swiftly, sapping her of her energy and morale. Radiation and chemotherapy did the rest of the job, obliterating her immunity. My grandma was relatively young; she didn’t deserve to die. No victim of cancer deserves to die. Her spiritual beliefs, and the rest of our family’s, were severely tested: was there no good in the world, only power and victims? Worse, cancer is a power you cannot usurp: you can try your best to survive but as long as even a single mutant cell remains in your body, it will get you in the end.
Scientists have worked tirelessly to put an end to this injustice, not reaching a definite conclusion but making healthy, if erratic, progress. In his Pulitzer Prize winning book The Emperor of All Maladies: A Biography of Cancer, Siddhartha Mukherjee documents this struggle. He asserts that “Ask any biological question, no matter how seemingly distant- what makes the heart fail, or why worms age, or even how birds learn songs- and you will end up, in fewer than six genetic steps, connecting with a proto-oncogene or tumour suppressor.” In other words, cancer causing or preventing agents. The Emperor of All Maladies, apart from being extremely relevant in a world where 7 million people died of cancer in 2010 alone, achieves what generations of authors have tried to achieve but failed miserably: it makes for a good read. The highly publicized death of Steve Jobs, CEO of Apple, has once again put cancer in the spotlight: pancreatic cancer claimed his life, and it is perhaps all the more important now for readers to understand and appreciate the illness.
Too many literary works, in particular non fictional ones, are simply and undeniably dull. Most medical write-ups groan with the weight of copious amounts of unneeded scientific jargon, making the reader have to consult an encyclopaedia a minimum of twenty five times before she reaches the end of the first page. Others adopt the monotonic voice of a textbook, perfectly understandable, everything beautifully explained, but full of information as sterile as a freshly disinfected operating theatre.
Mukherjee’s triumph is his ability to maintain the delicate equilibrium between fulfilling his purpose- to relate a concise history of cancer and attempted cures- and holding the reader’s attention. Quotations before every chapter, heartbreaking accounts of sufferers, researcher’s frustration and spectacular moments of hope add human interest to the too-sanitary concepts of DNA mutation and overactive cellular reproduction. A tale of a Persian queen who was one of the first recorded patients, gory details of amputation and accounts of searching for signs of this emperor of all maladies in far-flung graveyards throw in the pinch of glamour that turns a book from merely well-documented to a remarkable one that can be actively discussed in literary circles. It follows the journeys of a host of key characters involved in the fight against cancer, among them Mary Lasker, Sidney Farber, pioneers of chemotherapy, and Henry Kaplan who brought Hodgkin’s disease to the forefront.
If Mukherjee has written a scientific book, he has also penned a story of a ‘four thousand year old battle’, an epic where the enemy is your own body turning against you. It has been aptly titled ‘A Biography of Cancer’, a living thing with a mind of its own, unvanquished for millennia in its jeering tirade against humanity. Cancer is here a terrible villain, and while An Emperor also offers consolation and the anticipation of a conquest that seems far away, the disease becomes a personified creature mockingly watching as you crumble before its might: “Her illness had tried to humiliate her. It had made her anonymous and seemingly humourless; it had sentenced her to die an unsightly death… She had responded with vengeance, moving to be always one step ahead, trying to outwit it.” In fact, the book is a grown up version of the popular children’s edutainment series, Horrible Science. While it does not revel in everything macabre and gooey and squelchy, it is as varied a potpourri of information and experiences even as it deals with its ruthless subject, its tone crisp but lyrical simultaneously.
It deals not only with the discovery of multiple drugs, many failures and few successes, but also follows how cancer has been perceived by the public eye over the ages. It narrates how smoking, for instance, now known as a major killer, used to be recommended by doctors to ‘soothe the nerves’ -and is in fact still seen as the height of ‘cool’ among many young people. At this time in history lung cancer was attributed to car exhausts. It wonderingly muses on how Time magazine once refused to print an advertisement for a breast cancer support group because ‘breast’ and ‘cancer’ were censored words, the editor suggesting that they could call it instead a support group for ‘a disease of the chest wall’.
In a way, has come at the right moment. We are making massive strides everyday in the world of cancer treatment, yet even as our knowledge increases and awareness spreads, we realize how far away we are from completing this punishing journey. The time is ripe for the publishing of a biography of cancer; a gentle reminder not to grow too complacent but continue with our struggle against an enemy you cannot emerge victorious over but at best, contain- the very building blocks that make up your life essence.